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Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed)

National Institutes of Health

Opportunity #: PAR-24-129
Agency: National Institutes of Health
ALN (CFDA): 93.351, 93.310
Status: posted
Posted: Jan 22, 2024
Closes: Sep 25, 2026
Funding instrument: Cooperative Agreement
Category: Health
Cost sharing required: No

Who can apply

•Public and State controlled institutions of higher education

Other Eligible Applicants include the following:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. see NOFO for eligibility details

Synopsis

The purpose of this Notice of Funding Opportunity (NOFO) is to provide continuing support for specific pathogen-free (SPF) macaque colonies previously funded under the auspices of PAR-21-089 and PAR-18-669 that support Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) research. Breeding colonies are essential to sustain appropriate SPF macaques for research related to HIV/AIDS. Pedigree SPF macaques are free of certain viruses, which may confound the results of HIV/AIDS-related investigations or present a risk to the personnel who care for the animals. The SPF macaques are genetically characterized for major histocompatibility complex (MHC) class I types, because MHC class I genotypes have large effects on macaque immune responses to Simian Immunodeficiency Virus (SIV) that can induce AIDS in nonhuman primates (NHPs) and on human immune responses to HIV.

Contact

National Institutes of Health · grantsinfo@nih.gov

View full notice on Grants.gov ↗