Grant✓ Small businesses may apply
Avant Garde/Avenir Awards for Investigators Conducting High Risk/High Reward Research on HIV and Substance Use (or Substance Use Disorders) (DP1 Clinical Trial Optional)
National Institutes of Health
- Opportunity #
- PAR-27-026
- Agency
- National Institutes of Health
- ALN (CFDA)
- 93.279
- Status
- posted
- Posted
- Jun 9, 2026
- Closes
- Sep 25, 2028
- Funding instrument
- Grant
- Category
- Health
- Cost sharing required
- No
Who can apply
- •Special district governments
- •Native American tribal organizations (other than Federally recognized tribal governments)
- •Others (see text field entitled "Additional Information on Eligibility" for clarification)
- •Public and State controlled institutions of higher education
- •For profit organizations other than small businesses
- •Native American tribal governments (Federally recognized)
- •Public housing authorities/Indian housing authorities
- •Independent school districts
- •Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- •Private institutions of higher education
- •Small businesses
- •State governments
- •Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- •City or township governments
- •County governments
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Synopsis
The purpose of this notice of funding opportunity (NOFO) is to support innovative basic, clinical, translational, and implementation science research relevant to HIV and substance use. This initiative encourages high risk high impact transformative studies that advance knowledge and strategies for HIV prevention, diagnosis, treatment and virus suppression in people who use substances and/or have a substance use disorder.
Contact
National Institutes of Health · nidagmbemail@nida.nih.gov