Grant✓ Small businesses may apply
GREGoRi Technology Integration Center (U01, Clinical Trials Optional)
National Institutes of Health
Award ceiling
$2,250,000
Program funding
$3,000,000
- Opportunity #
- RFA-HG-27-012
- Agency
- National Institutes of Health
- ALN (CFDA)
- 93.172
- Status
- posted
- Posted
- Jun 18, 2026
- Closes
- Oct 30, 2026
- Funding instrument
- Cooperative Agreement
- Category
- Health
- Cost sharing required
- No
Who can apply
- •Native American tribal governments (Federally recognized)
- •Small businesses
- •Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- •Native American tribal organizations (other than Federally recognized tribal governments)
- •County governments
- •Public and State controlled institutions of higher education
- •Others (see text field entitled "Additional Information on Eligibility" for clarification)
- •Public housing authorities/Indian housing authorities
- •Private institutions of higher education
- •For profit organizations other than small businesses
- •Special district governments
- •City or township governments
- •Independent school districts
- •Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- •State governments
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Synopsis
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Technology Integration Center, which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of novel tools and strategies that facilitate rare disease diagnosis.
Contact
National Institutes of Health · nhgri-gregor@mail.nih.gov